Mathematical assessment of the role of pre-exposure prophylaxis on HIV transmission dynamics

作者：

Highlights：

• We model the impact of pre-exposure prophylaxis (PrEP) in an MSM population.

• The use of PrEP can induce backward bifurcation if its efficacy is not high enough.

• The combined use of HAART and PrEP can lead to HIV control in the population.

摘要

•We model the impact of pre-exposure prophylaxis (PrEP) in an MSM population.•The use of PrEP can induce backward bifurcation if its efficacy is not high enough.•The combined use of HAART and PrEP can lead to HIV control in the population.

论文关键词：HIV/AIDS,Pre-exposure prophylaxis (PrEP),Backward bifurcation,Equilibria,Stability,Reproduction number

论文评审过程：Received 8 December 2015, Revised 18 July 2016, Accepted 26 July 2016, Available online 30 August 2016, Version of Record 30 August 2016.

论文官网地址：https://doi.org/10.1016/j.amc.2016.07.043