Hepatitis C virus infection is blocked by HMGB1: A new nonlocal and time-delayed reaction–diffusion model

作者：

Highlights：

• We propose a new nonlocal and time-delayed reaction–diffusion equation model for hepatitis C virus infection.

• Threshold-type results are obtained for the spatially heterogeneous model with nonlocal time delay in a bounded domain.

• Travelling wave solutions are studied for the spatially homogeneous model in an unbounded domain.

摘要

•We propose a new nonlocal and time-delayed reaction–diffusion equation model for hepatitis C virus infection.•Threshold-type results are obtained for the spatially heterogeneous model with nonlocal time delay in a bounded domain.•Travelling wave solutions are studied for the spatially homogeneous model in an unbounded domain.

论文关键词：HCV,Nonlocal,Basic reproduction number,Travelling wave solutions,Threshold dynamics

论文评审过程：Received 15 March 2017, Revised 27 August 2017, Accepted 24 September 2017, Available online 5 November 2017, Version of Record 5 November 2017.

论文官网地址：https://doi.org/10.1016/j.amc.2017.09.046