Robust domain of attraction estimation for a tumor growth model

作者：

Highlights：

• An extensive parametric analysis for a cancer dynamical model is carried out.

• The cancer growth model incorporates commonly non considered terms.

• Necessary and sufficient conditions on the existence of equilibrium points are provided.

• A readily applicable methodology to compute regions of attraction is proposed.

• An estimation of the robust region of attraction is provided.

摘要

•An extensive parametric analysis for a cancer dynamical model is carried out.•The cancer growth model incorporates commonly non considered terms.•Necessary and sufficient conditions on the existence of equilibrium points are provided.•A readily applicable methodology to compute regions of attraction is proposed.•An estimation of the robust region of attraction is provided.

论文关键词：Cancer dynamical model,Chemoimmunotherapy,Domain of attraction estimation,Uncertain systems,Parametric uncertainties

论文评审过程：Received 13 November 2020, Revised 15 April 2021, Accepted 24 June 2021, Available online 11 July 2021, Version of Record 11 July 2021.

论文官网地址：https://doi.org/10.1016/j.amc.2021.126482