Reactor scale modeling of quorum sensing induced biofilm dispersal

作者：

Highlights：

• A 1D reactor scale model for quorum sensing controlled biofilm dispersal is presented and studied. It consists of 3 ODEs.

• The system, depending on parameters, will either attain (a) an upregulated steady state, or (b) a downregulated steady state, or (c) oscillate between down- and upregulated behaviour.

• Cases (a), (b) corrspond to continuous erosion, case (c) to almost instantaneous sloughing of biofilm.

• For comparison a simpler model for starvation controlled biofilm dispersal is included and analysed (2 ODEs).

摘要

•A 1D reactor scale model for quorum sensing controlled biofilm dispersal is presented and studied. It consists of 3 ODEs.•The system, depending on parameters, will either attain (a) an upregulated steady state, or (b) a downregulated steady state, or (c) oscillate between down- and upregulated behaviour.•Cases (a), (b) corrspond to continuous erosion, case (c) to almost instantaneous sloughing of biofilm.•For comparison a simpler model for starvation controlled biofilm dispersal is included and analysed (2 ODEs).

论文关键词：Biofilm,Active detachment,Dispersal,Mathematical model,Nutrient starvation,Quorum sensing

论文评审过程：Received 20 May 2021, Revised 15 August 2021, Accepted 7 November 2021, Available online 12 December 2021, Version of Record 12 December 2021.

论文官网地址：https://doi.org/10.1016/j.amc.2021.126792