Artificial intelligence methods for analysis of electrocardiogram signals for cardiac abnormalities: state-of-the-art and future challenges

摘要

Cardiovascular diseases (CVDs) in India and globally are the major cause of mortality, as revealed by the World Health Organization (WHO). The irregularities in the pace of heartbeats, called cardiac arrhythmias or heart arrhythmias, are one of the commonly diagnosed CVDs caused by ischemic heart disease, hypertension, alcohol intake, and stressful lifestyle. Other than the listed CVDs, the abnormality in the cardiac rhythm caused by the long term mental stress (stimulated by Autonomic Nervous System (ANS)) is a challenging issue for researchers. Early detection of cardiac arrhythmias through automatic electronic techniques is an important research field since the invention of electrocardiogram (ECG or EKG) and advanced machine learning algorithms. ECG (EKG) provides the record of variations in electrical activity associated with the cardiac cycle, used by cardiologists and researchers as a gold standard to study the heart function. The present work is aimed to provide an extensive survey of work done by researchers in the area of automated ECG analysis and classification of regular & irregular classes of heartbeats by conventional and modern artificial intelligence (AI) methods. The artificial intelligence (AI) based methods have emerged popularly during the last decade for the automatic and early diagnosis of clinical symptoms of arrhythmias. In this work, the literature is explored for the last two decades to review the performance of AI and other computer-based techniques to analyze the ECG signals for the prediction of cardiac (heart rhythm) disorders. The existing ECG feature extraction techniques and machine learning (ML) methods used for ECG signal analysis and classification are compared using the performance metrics like specificity, sensitivity, accuracy, positive predictivity value, etc. Some popular AI methods, which include, artificial neural networks (ANN), Fuzzy logic systems, and other machine learning algorithms (support vector machines (SVM), k-nearest neighbor (KNN), etc.) are considered in this review work for the applications of cardiac arrhythmia classification. The popular ECG databases available publicly to evaluate the classification accuracy of the classifier are also mentioned. The aim is to provide the reader, the prerequisites, the methods used in the last two decades, and the systematic approach, all at one place to further purse a research work in the area of cardiovascular abnormalities detection using the ECG signal. As a contribution to the current work, future challenges for real-time remote ECG acquisition and analysis using the emerging technologies like wireless body sensor network (WBSN) and the internet of things (IoT) are identified.