A multi-layered approach to protein data integration for diabetes research

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ObjectiveRecent advances in high-throughput experimental techniques have enabled many protein–protein interactions to be identified and stored in large databases. Understanding protein interactions is fundamental to the advancement of science and medical knowledge, unfortunately the scale of the requires an automated approach to analysis. We describe our graph-mining techniques to identify important structures within protein–protein interaction networks to aid in human comprehension and computerised analysis.

论文关键词:Protein interactions,Graph theory,Erdos–Renyi

论文评审过程:Received 1 December 2006, Revised 26 July 2007, Accepted 26 July 2007, Available online 14 September 2007.

论文官网地址:https://doi.org/10.1016/j.artmed.2007.07.009