Fully non-homogeneous hidden Markov model double net: A generative model for haplotype reconstruction and block discovery

摘要

ObjectiveIn the last decade, haplotype reconstruction in unrelated individuals and haplotype block discovery have riveted the attention of computer scientists due to the involved strong computational aspects. Such tasks are usually addressed separately, but recently, statistical techniques have permitted them to be solved jointly. Following this trend we propose a generative model that permits researchers to solve the two problems jointly.