Morphometric analysis of brain images with reduced number of statistical tests: A study on the gender-related differentiation of the corpus callosum

摘要

ObjectiveWe evaluate the feasibility of applying dynamic recursive partitioning (DRP), an image analysis technique, to perform morphometric analysis. We apply DRP to detect and characterize discriminative morphometric characteristics between anatomical brain structures from different groups of subjects. Our method reduces the number of statistical tests, commonly required by pixel-wise statistics, alleviating the effect of the multiple comparison problem.