Analysis of adverse drug reactions using drug and drug target interactions and graph-based methods
作者：
Highlights：
•
摘要
ObjectiveThe purpose of this study was to integrate knowledge about drugs, drug targets, and topological methods. The goals were to build a system facilitating the study of adverse drug events, to make it easier to find possible explanations, and to group similar drug–drug interaction cases in the adverse drug reaction reports from the US Food and Drug Administration (FDA).
论文关键词：Adverse drug reaction,Drug target,Drug target ontology,Clustering coefficient,Drug–drug interaction
论文评审过程：Received 15 August 2008, Revised 3 September 2009, Accepted 8 September 2009, Available online 3 December 2009.
论文官网地址：https://doi.org/10.1016/j.artmed.2009.11.002
