Identification of transcription factors that may reprogram lung adenocarcinoma
作者：
Highlights：
• The method can identify the core transcription factors that regulate lung adenocarcinoma associated genes.
• Seven core transcription factors are detected, and have been reported to relate to tumorigenesis of lung adenocarcinoma.
• The discovered functional core set may reverse malignant transformation and reprogram cancer cells.
摘要
•The method can identify the core transcription factors that regulate lung adenocarcinoma associated genes.•Seven core transcription factors are detected, and have been reported to relate to tumorigenesis of lung adenocarcinoma.•The discovered functional core set may reverse malignant transformation and reprogram cancer cells.
论文关键词：Lung adenocarcinoma,Transcription factor,Tumorigenesis,Greedy algorithm
论文评审过程：Received 19 December 2016, Revised 19 January 2017, Accepted 22 March 2017, Available online 1 April 2017, Version of Record 17 November 2017.
论文官网地址：https://doi.org/10.1016/j.artmed.2017.03.010
