Fast density-peaks clustering for registration-free pediatric white matter tract analysis

作者:

Highlights:

• We devise a fast density peak algorithm for data clustering that is able to automatically parcellate major WM tracts in a more efficient and accurate way than the existing clustering methods.

• The proposed clustering paves the possibility for tract-wise analysis on pediatric development in the native space with minimal human interactions. Compared with the popular atlas-based analysis derived from TBSS, our approach is free of additional skeletonization and registration steps that may introduce extra errors.

• We validate the effectiveness of both our clustering method and tract-wise analysis in two sections of experiments.

摘要

•We devise a fast density peak algorithm for data clustering that is able to automatically parcellate major WM tracts in a more efficient and accurate way than the existing clustering methods.•The proposed clustering paves the possibility for tract-wise analysis on pediatric development in the native space with minimal human interactions. Compared with the popular atlas-based analysis derived from TBSS, our approach is free of additional skeletonization and registration steps that may introduce extra errors.•We validate the effectiveness of both our clustering method and tract-wise analysis in two sections of experiments.

论文关键词:Fast clustering,White matter tracts,DTI,Pediatric development

论文评审过程:Received 30 September 2018, Revised 27 February 2019, Accepted 1 March 2019, Available online 2 March 2019, Version of Record 16 March 2019.

论文官网地址:https://doi.org/10.1016/j.artmed.2019.03.002