Mining heterogeneous network for drug repositioning using phenotypic information extracted from social media and pharmaceutical databases

作者：

Highlights：

• Drug repositioning with novel heterogeneous network mining.

• Extract phenotypic information from social media and pharmaceutical databases.

• Utilize multiple data sources to detect medical relationship.

• Evidence-based evaluation of discovered repositioning drugs.

摘要

•Drug repositioning with novel heterogeneous network mining.•Extract phenotypic information from social media and pharmaceutical databases.•Utilize multiple data sources to detect medical relationship.•Evidence-based evaluation of discovered repositioning drugs.

论文关键词：Drug repositioning,Heterogeneous network mining,Online health community,Phenotype,Social media

论文评审过程：Received 1 June 2018, Revised 24 February 2019, Accepted 5 March 2019, Available online 9 March 2019, Version of Record 4 April 2019.

论文官网地址：https://doi.org/10.1016/j.artmed.2019.03.003