A methodology based on multiple criteria decision analysis for combining antibiotics in empirical therapy

作者：

Highlights：

• A method for selecting empiric antibiotic therapy can be based on a optimization model.

• Multiple criteria are needed for development of new antibiotic combinations.

• This method can be used to design and adapt clinical protocols to local settings.

摘要

•A method for selecting empiric antibiotic therapy can be based on a optimization model.•Multiple criteria are needed for development of new antibiotic combinations.•This method can be used to design and adapt clinical protocols to local settings.

论文关键词：Multiple criteria decision analysis,Clinical decision support,Combination therapy,Multiobjective-optimization,Empiric antimicrobial therapy

论文评审过程：Received 27 September 2018, Revised 24 September 2019, Accepted 1 November 2019, Available online 13 November 2019, Version of Record 30 December 2019.

论文官网地址：https://doi.org/10.1016/j.artmed.2019.101751