Near-optimal insulin treatment for diabetes patients: A machine learning approach

作者:

Highlights:

• We present a diabetes control based on a stochastic model of blood glucose level (BGL).

• We introduce the health reward function (HRF) which numerically grades a BGL.

• HRF and the stochastic model give rise to a Markov Decision Process (MDP).

• The solution to MDP provides an optimal policy which leads to healthy simulated BGL.

• The method is equally effective for non-standard and rare diabetic patients.

摘要

•We present a diabetes control based on a stochastic model of blood glucose level (BGL).•We introduce the health reward function (HRF) which numerically grades a BGL.•HRF and the stochastic model give rise to a Markov Decision Process (MDP).•The solution to MDP provides an optimal policy which leads to healthy simulated BGL.•The method is equally effective for non-standard and rare diabetic patients.

论文关键词:

论文评审过程:Received 15 July 2019, Revised 17 June 2020, Accepted 23 June 2020, Available online 29 June 2020, Version of Record 24 July 2020.

论文官网地址:https://doi.org/10.1016/j.artmed.2020.101917