Network differentiation: A computational method of pathogenesis diagnosis in traditional Chinese medicine based on systems science

作者：

Highlights：

• We introduce pathogenesis network to represent Bing Ji in traditional Chinese medicine in the form of the digraph.

• We propose a computational method called network differentiation to simulate the pathogenesis diagnosis.

• We state and prove some theorems for the optimization of network differentiation.

• We introduce the strategy of consistency evaluation to evaluate the performance of network differentiation.

摘要

•We introduce pathogenesis network to represent Bing Ji in traditional Chinese medicine in the form of the digraph.•We propose a computational method called network differentiation to simulate the pathogenesis diagnosis.•We state and prove some theorems for the optimization of network differentiation.•We introduce the strategy of consistency evaluation to evaluate the performance of network differentiation.

论文关键词：Traditional Chinese medicine,Graph theory,Network differentiation,systems biology,artificial intelligence

论文评审过程：Received 30 November 2020, Revised 12 April 2021, Accepted 28 June 2021, Available online 3 July 2021, Version of Record 17 July 2021.

论文官网地址：https://doi.org/10.1016/j.artmed.2021.102134