Evolutionary deep feature selection for compact representation of gigapixel images in digital pathology

作者:

Highlights:

• Deep learning increasingly influences in digital pathology workflow.

• Compactly representing a WSI to enable computational pathology is an urgent need.

• Evolutionary computation can optimize the output of pre-trained deep networks.

• Irrelevant or redundant features are removed to encompass salient features.

• Compact feature vectors achieved 93% classification accuracy.

摘要

•Deep learning increasingly influences in digital pathology workflow.•Compactly representing a WSI to enable computational pathology is an urgent need.•Evolutionary computation can optimize the output of pre-trained deep networks.•Irrelevant or redundant features are removed to encompass salient features.•Compact feature vectors achieved 93% classification accuracy.

论文关键词:Digital pathology,Whole slide images,Image representation,Evolutionary computation

论文评审过程:Received 26 September 2021, Revised 13 June 2022, Accepted 14 July 2022, Available online 25 July 2022, Version of Record 2 August 2022.

论文官网地址:https://doi.org/10.1016/j.artmed.2022.102368