A diagnostic prediction framework on auxiliary medical system for breast cancer in developing countries

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摘要

Due to the complexity of the tumor and a large amount of patient information, an intelligent system is used to filter and extract hidden information, which will be beneficial to make accurate diagnostic decisions. The treatment and prognosis of breast cancer depend on the tumor stage. The PET-CT image can clearly show the lesion area and lesion range, especially for advanced-stage patients. Images and blood tests are crucial for accurate staging, tumor monitoring, and providing guided treatment plans. Multi-source data collaborative analysis can mine hidden attributes to provide a more intelligent treatment plan. This paper proposes a framework for predicting the diagnosis of the patient’s disease by combining images and labeling parameters. The blood test data and image data of patients are filtered based on the establishment of the medical decision-making module. The module selects detection indicators that correlate with tumor staging for analysis and trains a prediction model to assist doctors in providing a second diagnosis. The proposed framework for breast cancer diagnosis was tested on 5470 patient data from three well-known hospitals in China. The test results indicate that it performs well in diagnosing cancer staging with a prediction accuracy of 0.88.

论文关键词:Breast cancer,Cancer staging,Big data,Tumor markers,Assist second diagnosis,Medical decision-making

论文评审过程:Received 24 July 2020, Revised 14 August 2021, Accepted 30 August 2021, Available online 8 September 2021, Version of Record 16 September 2021.

论文官网地址:https://doi.org/10.1016/j.knosys.2021.107459