Classification of BMD and ADHD patients using their EEG signals

摘要

Bipolar Mood Disorder (BMD) and Attention Deficit Hyperactivity Disorder (ADHD) patients mostly share clinical signs and symptoms in children; therefore, accurate distinction of these two mental disorders is a challenging issue among the psychiatric society. In this study, 43 subjects are participated including 21 patients with ADHD and 22 subjects with BMD. Their electroencephalogram (EEG) signals are recorded by 22 electrodes in two eyes-open and eyes-closed resting conditions. After a preprocessing step, several features such as band power, fractal dimension, AR model coefficients and wavelet coefficients are extracted from recorded signals. This paper is aimed to achieve a high classification rate between ADHD and BMD patients using a suitable classifier to their EEG features. In this way, we consider a piece wise linear classifier which is designed based on XCSF. Experimental results of XCSF-LDA showed a significant improvement (86.44% accuracy) compare to that of standard XCSF (78.55%). To have a fair comparison, the other state-of-art classifiers such as LDA, Direct LDA, boosted JD-LDA (BJDLDA), and XCSF are assessed with the same feature set that finally the proposed method provided a better results in comparison with the other rival classifiers. To show the robustness of our method, additive white noise with different amplitude is added to the raw signals but the results achieved by the proposed classifier empirically confirmed a higher robustness against noise compare to the other classifiers. Consequently, the proposed classifier can be considered as an effective method to classify EEG features of BMD and ADHD patients.