Discovery of functional protein groups by clustering community links and integration of ontological knowledge
作者:
Highlights:
• Protein-to-protein interactions constitute a major element of biology.
• We use ontologies as a useful source of structured knowledge.
• Clustering the links shared by proteins reveals their shared/multiple function nature.
• Combining link clustering with databases, provides a deeper insight into protein function.
摘要
•Protein-to-protein interactions constitute a major element of biology.•We use ontologies as a useful source of structured knowledge.•Clustering the links shared by proteins reveals their shared/multiple function nature.•Combining link clustering with databases, provides a deeper insight into protein function.
论文关键词:Cystinosis,Protein-to-protein interactions,Clustering,Ontologies
论文评审过程:Available online 25 March 2013.
论文官网地址:https://doi.org/10.1016/j.eswa.2013.03.027