Real-time and decision taking selection of single-particles during automated cryo-EM sessions based on neuro-fuzzy method

作者：

Highlights：

• Intelligent TEM control allows automated, unsupervised and efficient cryo-EM data collection.

• The system includes ANFIS-based detection of single-particles during the automated sessions.

• A classic FIS system makes appropriate decisions during the session, as would an expert microscopist.

摘要

•Intelligent TEM control allows automated, unsupervised and efficient cryo-EM data collection.•The system includes ANFIS-based detection of single-particles during the automated sessions.•A classic FIS system makes appropriate decisions during the session, as would an expert microscopist.

论文关键词：Cryo-electron microscopy,Decision support systems,Fuzzy logic,Image processing,Single-particle analysis

论文评审过程：Received 10 June 2015, Revised 12 February 2016, Accepted 14 February 2016, Available online 19 February 2016, Version of Record 7 March 2016.

论文官网地址：https://doi.org/10.1016/j.eswa.2016.02.018