Outlier based literature exploration for cross-domain linking of Alzheimer’s disease and gut microbiota

作者：

Highlights：

• The methodology supports knowledge discovery by cross-domain literature exploration.

• Outlier detection and expert assisted filtering fasten bridging terms identification.

• Nitric Oxide Synthase was found to link Alzheimer’s disease and gut microbiota.

• Results point out the role of immune system in neurodegenerative diseases.

摘要

•The methodology supports knowledge discovery by cross-domain literature exploration.•Outlier detection and expert assisted filtering fasten bridging terms identification.•Nitric Oxide Synthase was found to link Alzheimer’s disease and gut microbiota.•Results point out the role of immune system in neurodegenerative diseases.

论文关键词：Literature-based discovery,Outlier detection,Alzheimer’s disease,Gut microbiome

论文评审过程：Received 1 February 2017, Revised 7 May 2017, Accepted 9 May 2017, Available online 11 May 2017, Version of Record 25 May 2017.

论文官网地址：https://doi.org/10.1016/j.eswa.2017.05.026