A Deep Active Survival Analysis approach for precision treatment recommendations: Application of prostate cancer

作者:

Highlights:

• Proposed a novel survival analysis approach for high dimensional clinical data.

• Our survival analysis approach is based on deep learning and active learning.

• Developed a new sampling strategy for survival active learning.

• Applied our method on SEER-Medicare prostate cancer data for two racial groups.

• Results indicate that our method significantly improve the performance of baseline.

摘要

•Proposed a novel survival analysis approach for high dimensional clinical data.•Our survival analysis approach is based on deep learning and active learning.•Developed a new sampling strategy for survival active learning.•Applied our method on SEER-Medicare prostate cancer data for two racial groups.•Results indicate that our method significantly improve the performance of baseline.

论文关键词:Survival analysis,Deep learning,Active learning,Treatment recommendation,Electronic health records,Prostate cancer

论文评审过程:Received 10 May 2018, Revised 12 July 2018, Accepted 30 July 2018, Available online 31 July 2018, Version of Record 10 August 2018.

论文官网地址:https://doi.org/10.1016/j.eswa.2018.07.070