AnomalP: An approach for detecting anomalous protein conformations using deep autoencoders

作者:

Highlights:

• A new approach for detecting anomalous protein conformations is introduced.

• It uses deep autoencoders for encoding information about proteins from a superfamily.

• Experiments confirm a very good performance of the proposed approach.

摘要

•A new approach for detecting anomalous protein conformations is introduced.•It uses deep autoencoders for encoding information about proteins from a superfamily.•Experiments confirm a very good performance of the proposed approach.

论文关键词:Proteomics,Deep learning,Autoencoders,Anomaly detection

论文评审过程:Received 22 August 2019, Revised 29 August 2020, Accepted 28 September 2020, Available online 29 September 2020, Version of Record 6 October 2020.

论文官网地址:https://doi.org/10.1016/j.eswa.2020.114070