Stochastic Local Search for the Direct Aperture Optimisation Problem

作者：

Highlights：

• Combinatorial optimisation in radiation therapy for cancer treatment.

• Deliverable treatment plans solving the Direct Aperture Optimisation problem.

• Competitive Stochastic local search algorithm for Direct Aperture Optimisation.

• Fluence-map representation for the Direct Aperture Optimisation Problem.

摘要

•Combinatorial optimisation in radiation therapy for cancer treatment.•Deliverable treatment plans solving the Direct Aperture Optimisation problem.•Competitive Stochastic local search algorithm for Direct Aperture Optimisation.•Fluence-map representation for the Direct Aperture Optimisation Problem.

论文关键词：Direct aperture optimisation problem,Intensity modulated radiation therapy,Stochastic local search,Prostate cancer treatment,Fluence map-based neighbourhood

论文评审过程：Received 3 December 2020, Revised 30 March 2021, Accepted 12 May 2021, Available online 24 May 2021, Version of Record 7 June 2021.

论文官网地址：https://doi.org/10.1016/j.eswa.2021.115206