A fractional-order model for Ebola virus infection with delayed immune response on heterogeneous complex networks

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摘要

Most of the biological systems have long-range temporal memory and modeling of such systems by fractional-order differential equations has more advantages than classical models with integer-orders. In this paper, we provide a fractional-order Ebola virus epidemic model with delayed immune response on heterogeneous complex networks. The time-delay is introduced in the cytotoxic T-lymphocyte (CTLs) term. Based on fractional Laplace transform, some conditions on stability are derived for the model. The analysis shows that the fractional-order time-delay can effectively enrich the dynamics and strengthen the stability condition of fractional-order infection model. Finally, the derived theoretical results are justified by some numerical simulations.

论文关键词:Ebola virus,Complex networks,CTL response,Stability,Time-delay

论文评审过程:Received 7 April 2017, Revised 31 October 2017, Available online 2 December 2017, Version of Record 18 April 2018.

论文官网地址:https://doi.org/10.1016/j.cam.2017.11.032